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9 October, Tuesday, Day 1

10:00 – 13:00 Scientific storytelling workshop
From pen to publication: the journey of a scientific paper
14:00 – 18:00   Registration
14:15 - 14:30 Opening ceremony
Session 1: DNA methylation
chair: Tamás Arányi
14:30 – 15:00 Etienne Bucher
Epigenetic regulation of retrotransposon mobility by RNA polymerase II
15:00 – 15:15 Anna Stroynowska-Czerwinska
Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications
15:15 – 15:45 Cristina Cardoso
Methyl-cytosine binding proteins: guardians of the epigenome?
15:45 – 16:15 Coffee break
16:15 – 16:30 Tuncay Baubec
Understanding the dynamic cross-talk between DNA methylation and histone modifications in stem cells
16:30 – 16:45 Adele Murrell
Genomic imprinting and the Mammary Gland
16:45 – 17:15 Deborah Bourc’his
Maternal epigenetic contribution to embryonic genome activation
17:15 – 17:30 Technical break
17:30 – 18:30

Keynote lecture
chair: Petra Hajkova

Adrian Bird
The genetics and epigenetics of Rett syndrome

19:00 – 22:00 Welcome reception
Öbölház; 1117 Budapest, Kopaszi gát 1.

10 October, Wednesday, Day 2

08:30 – 09:30 Breakfast with the invited speakers (Danubius Hotel Flamenco; 1113 Budapest, Tas vezér u. 3-7.) Available only for those who have secured their places beforehand.
09:00 – 10:00 Registration
Session 2: Chromatin structure
chair: Lóránt Székvölgyi
10:00 – 10:30 Ferenc Müller
How do the first genes get switched on in the embryo?
10:30 – 10:45 Florian Richter
Systematic and comprehensive mapping of H2B modifications by limited trypsin proteolysis and overlapping MS identify a wealth of novel non-canonical histone marks.
10:45 – 11:00 Endre Sebestyén
Chromatin fractionation sequencing for the detection of early heterochromatin alterations in Hutchinson-Gilford progeria syndrome
11:00 – 11:30 Coffee break
11:30 – 12:00 Robert Schneider
Novel Players in Chromatin
12:10 – 12:15 Marion Crespo
Proteomics study of acylations in mouse spermatogenesis and yeast sporulation
12:15 – 12:45 Evi Soutoglou
Fundamental differences in spatial regulation of Double Strand break Repair in mouse and human pericentric heterochromatin
12:45 – 14:30 Lunch break
14:30 – 17:00 Poster session I
Coffee wil be served 16:00
Session 3: Developmental epigenetics
chair: Orsolya Symmons
17:00 – 17:30 Petra Hajkova
Epigenetic reprogramming in mouse germ line
17:30 – 17:45 Courtney Hanna
Epigenetic regulation of allelic-specific expression during embryonic development
17:45 – 18:00 Heinrich Leonhardt
TET1 drives global DNA demethylation via DPPA3-mediated inhibition of maintenance methylation
18:00 – 18:15 Raffaella Santoro
NoRC complex regulates genome architecture of ground state pluripotent stem cells
18:15 – 18:30 Orsolya Symmons
Quantitative imaging of allele-specific gene expression in mouse tissues
18:30 – 19:00 Maria Elena Torres-Padilla
Epigenetic mechanisms in early mammalian development
20:00 – Beer session / Meet the lecturers
Cactus Juice; 1061 Budapest, Jókai tér 5.


11 October, Thursday, Day 3


08:30 – 09:30 Breakfast with the invited speakers (Danubius Hotel Flamenco; 1113 Budapest, Tas vezér u. 3-7.) Available only for those who have secured their places beforehand. 
Session 4: Transcription and epigenetics
chair: Bálint László Bálint
10:00 – 10:30 László Tora
Co-translation drives the assembly of mammalian transcription regulatory multi-subunit complexes
10:30 – 10:45 Patrizia Filetici
Respiratory role for Gcn5 and DUB- Ubp8
10:45 – 11:00 Luisa Di Stefano
A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons
11:00 – 11:30 Coffee break
11:30 – 12:00 Duncan Odom
Evolution of transcriptional regulation across mammals
12:00 – 12:15 María Inmaculada Calvo Sánchez
A role for ROS in the dynamic regulation of DNA methylation
12:15 – 12:45 Alexander Stark
Decoding transcriptional regulation in Drosophila
12:45 14:30
Lunch break
14:30 – 16:30 Poster session 2
Coffee wil be served 16:00
Session 5: Metabolism and epigenetics
chair: Ferenc Müller
16:30 - 17:00
John Andrew Pospisilik
Epigenetic underpinnings of common complex disease
17:00 – 17:30 Tim Osborne
Genome-wide analysis of human adipocytes reveal gene expression and chromatin signatures involved in fat distribution in premenopausal women
17:30 – 17:45 Antonio Galvao
How maternal obesity affects the Oocyte epigenome and preimplantation embryos
17:45 – 18:15 László Nagy (IUBMB)
The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory
18:15 – 18:30 Georgina Blake
Investigating the epigenetic mechanism behind transgenerational inheritance in germ cells of mice with abnormal folate metabolism
18:30 – 19:00 Sarah Wickström
Mechanoadaptation at the nucleoskeleton-chromatin interface
20:30 – Gala dinner
Gundel Restaurant; 1146 Budapest, Gundel K. út 4.

12 October, Friday, Day 4

08:30 – 09:30   Breakfast with the invited speakers (in speakers’ hotel, maximum 3 student/speaker, first come/first served)
Session 6: non-coding RNA
chair: Claire Rougeulle
10:00 – 10:30 Claire Rougeulle
Functional and mechanistic plasticity of long noncoding RNAs: lessons from X-inactivation
10:30 – 10:45 Miguel Casanova
Exploring the contribution of human retroelements in species-specific mechanisms of X chromosome inactivation
10:45 – 11:00 Maud Borensztein
X-chromosome reprogramming during embryonic development
11:00 – 11:30 Coffee break
11:30 – 12:00 Eric Miska
The plasticity, epigenetic variation and inheritance in the Malawi cichlid adaptive radiation
12:00 – 12:15 Lóránt Székvölgyi
Chromosomal R-loops in the context of chromatin structure
12:15 – 12:30 Petros Tzerpos
Chromatin state dynamics and gene regulation in macrophages during inflammatory response
12:30 – 13:00 Mariusz Nowacki
RNA-guided epigenetic programming of genome rearrangement in Paramecium
13:00 – 13:15 Concluding remarks
13:15 – 14:30 Farewell snack
14:30 - 17:30
Scientific storytelling workshop
Science communication & public engagement: beyond the scientific article

Posters list

Each poster might be mounted during the whole Conference. The recommended poster size is a standing A/0 (84 cm x 119 cm) as the size of the poster board is 90 cm at width and 120 cm at height. Posters left on the boards after the removal deadline will be removed by the organisers.
Mounting: 9 October, from 14:00
Removal: 12 October, before 13:00

Technical instructions:

Posters should be prepared for standard STANDING (PORTRAIT) A/0 size (84 x 119 cm – 1 sqm). PLEASE DO NOT PRINT A LANDSCAPE POSTER!
The organisers provide pins to mount your poster to the board at the conference venue and they will be at your disposal if you need help.

ID Title of lecture / Author


Veronique Adoue
Epigenetic regulation of T(reg) cell development and functions


Tayfun Hilmi Akbaba
MiRNAs as possible modulators in the pathogenesis of systemic auto inflammatory diseases


Mirit Aladjem
Chromatin interactions coordinate transcriptional activity with genome duplication


Veronika Antonyová
Inhibition of TET protein 1 activity by iron chelators of hydrazone class


Yennyfer Arancibia
The co-repressor complex mSin3A/HDAC1 is involved in the down-regulation of CRTC2 target genes during B cell differentiation


Tamás Arányi
L-DOPA administration induces DNA methylation loss in the striatum of a rat tic model and reveals potential new targets for Tourette syndrome treatment


Judit Balog
Monosomy of SMCHD1 as a result of interstitial chromosome 18p deletions causes somatic derepression of the subtelomeric D4Z4 macrosatellite repeat on chromosomes 4 and 10


László Bodai
The effects of specific histone methylations and potential role of bivalent chromatin regulation in Huntington’s disease


Dóra Bojcsuk
Alternative super-enhancers result in similar gene expression in different tissues


Beáta Boros-Oláh
RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases


Rosevalentine Bosire
Accessibility of native chromatin to small molecules through biophysical spectacles


Déborah Bouvier
Histone chaperone-independent function of HIRA in transcription regulation following UVC damage


Edith Breton
NEGR1 epivariations are associated with maternal hyperglycemia in pregnancy and offspring neurodevelopment at 3 years of age


Tereza Brezinova
New fluorescent iron chelators with cytotoxic effects and imaging possibilities


Sathishkumar Chandrakumar
Association of altered LncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence and inflammation in patients with type 2 diabetes of Asian Indian Phenotype


Aimee Rodica Chis
Time dependent expression of mmu-miR-195 in various mouse tissues


Suyeon Cho
KLHL4, a novel p53 target gene, activates p21WAF/CDKN1A and inhibits cell proliferation


Margit Cichna-Markl
DNA methylation status of CDKN2A promoter and exon 2 in breast cancer tissues and cell lines


Catherine Corbel
Critical role of DXZ4 locus in the 3D structure of the inactive X chromosome and in facultative escape from XCI in vivo


Zsolt Czimmerer
STAT6 transcription factor-mediated direct repression of inflammatory enhancers limits inflammasome activation in alternatively polarized macrophages


Thomas Dahlet
The transcription factor E2F6 represses germline genes by recruiting DNA methylation to gene promoters


Mathieu Dalvai
Environmentally-relevant contaminants synergistically perturb the spermatogonial stem cell epigenome and transcriptome, and are offset by omega-3 fatty acids


Mona Dawood
Epigenetics and collateral sensitivity in cancer


Christina Demetriadou
Deciphering the role of NAA40 acetyltransferase in gene regulation and colorectal cancer


Hannah Demond
Analysing DNA methylation progression of mouse oocytes in vitro


Adeline Divoux
Genome wide analysis of human adipocytes revealed a new gene potentially involved in fat distribution in premenopausal women


Fabio D'Orazio
Epicenetic inheritance: onset of chromatin signature during embryonic germ line formation in zebrafish


Edina Erdős
COUP-TFII (super) enhancers are associated with CTCF mediated interactions in cancer cell lines


Amanda Evans
Elucidating key regulators in temporal regulation of early endoderm development in zebrafish


Anikó Faragó
A specific acetylation mimicking point mutation of H3.3A ameliorates Huntingtin induced phenotypes in a fly model


Sara Fernandes
6-methyl Adenine: a ubiquitous eukaryotic modification that is established during early development


Sandra Fernández Martos
Direct hydroxylation of methylated cytosines in a DNA fragment in vitro by a transient ROS production


Valérie Gagné-Ouellet
Identification of placental epigenetic variation associated with adiposity in early-childhood.


Gergely Nagy
Dissecting the hierarchical regulatory element networks of macrophages


Nikolaos Giannakis
Epigenomic, trancriptomic and lipidomic approaches exhibit the dynamic changes following cardiotoxin-induced muscle tissue injury and repair in mice


László Halász
IL-4/STAT6 signaling pathway dependent chromatin remodeling induces the rearrangement of LPS-activated p65 cistrome, leading to synergistic transcriptional activation of a specific gene subset


Regan Hayward
Epigenetic changes in Chlamydia-infected host cells


Clara Hechenberger
Modulation of PAX5 protein levels using conditional degron-based systems


Saadat Hussain
Identification and analysis of silencer elements in T cells and leukemia


László Imre
H2A.Z: stable or not stable, that is the question


Muñoa Iraia
Chip sequencing reveals changes in the genomic distribution of epigenetic repressive mark H3K27me3, at ICR/DMRs of imprinted genes induced by morphine in mouse embrionic stem cells (mESC)


Paulina Kołodziej
Ten-eleven translocation protein 1 regulates human dermal fibroblast proliferation, apoptosis and autophagy in an age-related manner


Katarina Kouter
DNA methylation pattern analysis in suicide victims


Jure Krasić
Influence of epigenetic agents on mouse teratoma development in vitro


Carole LaBonne
Epigenetic mechanisms underlying the evolution of a GRN Controlling pluripotency and Neural Crest formation.


Lorane Le Franc
Epigenetic regulation of development: RNA methylation in a distant model: the oyster Crassostrea gigas.


Manuela Leo
Ubiquitin protease Ubp8 is necessary for budding yeast respiration


Huaixing Li
GRK5-rs10886471 is associated with GRK5 gene expression by affecting DNA methylation in human adipose tissue


Jiri Kohoutek
Role of CDK12 in the regulation of DNMT1 activity by altering expression of miR-152


Donia Macartney-Coxson
Changes in DNA methylation within the HIF3A gene after weight-loss in individuals with severe obesity either undergoing dietary intervention or gastric bypass.


Donia Macartney-Coxson
Interplay of DNA methylation and transcription in the jejunum in type-two diabetes


Monika Madej
Impact of mitochondrial mutations on the metabolites-dependent epigenetic profile


Myriam Merz
The impact of early life adversity on mitochondrial function


Steven Millership
Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice


Alexandra Moatar
Age dependent expression of mmu-miR-19a in mouse tissues


George Muscat
Crosstalk between Protein arginine methyltransferase 6 and Estrogen Signalling in Breast Cancer: an epigenetic role in endocrine resistance?


Ji-Won Nam
STAT1/2-mediated high order chromatin enhances therapeutic efficacy through viral mimicry in hepatocellular carcinoma


Péter Nánási
Large-scale histone redistribution induced by Doxorubicin in Jurkat cells


Attila Oravecz
Transcription factor and chromatin dynamics in interphase and mitosis


Magdalena Owczarz
Aging-related alterations in the expression of SIRT6 in human peripheral blood mononuclear cells are associated with the significant changes in miRs expression


Lilla Ozgyin
Functional genomic variability of human B-lymphoblastoid cell lines with implications in pharmacogenomic research


Inga Patarcic
Predicting enhancer-gene associations using ensemble learning approaches


Sandra Piquet
The histone chaperone FACTcoordinates H2A.X-dependent signaling and repair of DNA damage


Anabelle Planques
Epigenetic regulations during Platynereis dumerilii development and regeneration


Francisca Salas-Perez
Analysis of DNA methylation in longevity pathways and its possible association with metabolic disorders


Rafael Sampaio
The Role of H3K9me2 on bovine nuclear reprogramming: how it modulates the epigenetic barrier


Flavia Santa-Cecília
Crotalphine modulates HDAC activity and DNA methylation in a model of inflammatory pain


Victoria Sarne
Gender differences in promoter methylation of selected target genes in
non-small cell lung cancer


Gintare Sendzikaite
A mutation within the PWWP domain alters chromatin targeting of DNMT3A


Ovidiu Sirbu
Plasma microRNA expression profiles in Parkinson's disease


Ji-Yang Song
SIRT1 gene transcription activation by HIC2 may protects heart from ischemia/reperfusion injury


Manon Tanguy
Investigating the role of DNA methylation in tissue differentiation with a Dnmt3aKO mouse model.


Ágnes Tantos
Long non-coding RNAs in histone methylation


Daniela Torres Campana
Epigenetic control of a maternal gene essential for sperm chromatin remodeling at fertilization


Erzsébet Tóth
Strand-specific R-loop identification in PISTILLATA floral homeotic regulation gene of Arabidopsis thaliana and it’s expression regulating by R-loops and NDX protein


Judit Vágó
Examination of DNA and histone methylation in different chondrogenic models


Giedre Valiuliene
Investigation of novel epigenetic therapy possibilities in acute promyelocytic leukemia treatment


Syed Shan-a-Ali Zaidi
Gem-In-Hels (Geminivirus-Induced-Helitrons): a novel method of capturing and sequencing rolling circle-replicating Helitron transposons


Katja Zappe
Comparison of assays for the determination of the MGMT promoter methylation status in glioblastoma


Máté Varga
Defective pseudouridylation results in impaired differentiation during zebrafish development


Elena Ivanova
DNA methylation analysis of human blastocyst obtained by two different ART protocols


Ada Jimenez-Gonzalez
dCas9-Eed fusion protein as a tool to target H3K27 trimethylation in zebrafish embryos

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